Society for NeuroOncology
VAL-083 inhibits proliferation of a panel of eight glioblastoma stem cells: Downregulation of BRD4 as a novel anti-neoplastic mechanism
AACR Annual Meeting 2018
Dianhydrogalactitol (VAL-083) has a distinct mechanism of action that suggests combination with PARP inhibitors as an effective therapeutic strategy
AACR Annual Meeting 2018
Dianhydrogalactitol (VAL-083) has the potential to overcome major challenges in the treatment of DIPG
AACR Annual Meeting 2018
An open-label, biomarker driven, Phase 1/2 study of dianhydrogalactitol (VAL-083) with radiation therapy in patients with newly diagnosed MGMT-unmethylated GBM
AACR Annual Meeting 2018
Phase 2 study of dianhydrogalactitol (VAL-083) in patients with bevacizumab-naïve recurrent glioblastoma, MGMT-unmethylated
Society for NeuroOncology
Dianhydrogalactitol (VAL-083) overcomes chemoresistance in pediatric malignant brain tumors and displays synergy with topoisomerase inhibitors
Society for NeuroOncology
The distinct cytotoxic mechanism of dianhydrogalactitol (VAL-083) overcomes chemoresistance and provides new opportunities for combination therapy in the treatment of glioblastoma
Society for NeuroOncology
Clinical Trials with dianhydrogalactitol (VAL-083) in MGMT-unmethylated Glioblastoma
AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
DNA damaging agent dianhydrogalactitol (VAL-083) targets HR repair pathway and suggests combination therapy with topoisomerase and PARP inhibitors
AACR Special Conference: Addressing Critical Questions in Ovarian Cancer Research and Treatment
Distinct mechanism of action of DNA damaging agent dianhydrogalactitol (VAL-083) suggests combination therapy with PARP inhibitors